2-hydroxy and 4-hydroxy glycolipids and their derivatives

A glycolipid of formula (I), or a salt thereof,

• wherein:
• A is a monosaccharide, a disaccharide, a trisaccharide, or an amine or thiol derivative thereof;
• B is
• L1 is C2-18alkylene or C2-18alkenylene;
• n is 0 or 2;
• RZ is hydrogen, C1-6alkyl, C1-6haloalkyl, G1a, —C1-6alkylene-G1a, —C1-6alkylene-RY, or
• L2, at each occurrence, is C2-18alkylene or C2-18alkenylene;
• n″, at each occurrence, is 0 or 2;
• RZ″, at each occurrence, is hydrogen, C1-6alkyl, C1-6haloalkyl, G1a″, —C1-6alkylene-G1a″, or —C1-6alkylene-RY″;
• RY, at each occurrence, is —OC1-4alkyl, —OC1-4haloalkyl, —OH, cyano, —SH, —SC1-4alkyl, —SC1-4haloalkyl, —SG1a, —NH2, —NHC1-4alkyl, —NHG1a, —N(C1-4alkyl)2, —N(G1a)2, —C(O)OG1a, —C(O)OC1-4alkyl, —C(O)NH2, —C(O)NHC1-4alkyl, —C(O)N(C1-4alkyl)2, —C(O)NHG1a, —C(O)N(G1a)2, —SO2C1-4alkyl, —SO2G1a, —SO2NH2, —SO2NHC1-4alkyl, or —SO2N(C1-4alkyl)2;
• RY″, at each occurrence, is —OC1-4alkyl, —OC1-4haloalkyl, —OH, cyano, —SH, —SC1-4alkyl, —SC1-4haloalkyl, —SG1a″, —NH2, —NHC1-4alkyl, —NHG1a″, —N(C1-4alkyl)2, —N(G1a″)2, —C(O)OG1a″, —C(O)OC1-4alkyl, —C(O)NH2, —C(O)NHC1-4alkyl, —C(O)N(C1-4alkyl)2, —C(O)NHG1a″, —C(O)N(G1a″)2, —SO2C1-4alkyl, —SO2G1a″, —SO2NH2, —SO2NHC1-4alkyl, or —SO2N(C1-4alkyl)2;
• and
• G1a and G1a″, at each occurrence, are independently a C3-8cycloalkyl, a 4- to 12-membered heterocyclyl, a 6- to 12-membered aryl, or a 5- to 12-membered heteroaryl, wherein G1a and G1a″ are independently optionally substituted with 1-5 substituents independently selected from the group consisting of halogen, oxo, C1-4alkyl, —OC1-4alkyl, —OC1-4haloalkyl, —OH, —SC1-4alkyl, —SC1-4haloalkyl, —SH, —NO2, —NH2, —NHC1-4alkyl, —N(C1-4alkyl)2, cyano, —C(O)OC1-4alkyl, —C(O)NH2, —C(O)NHC1-4alkyl, —C(O)N(C1-4alkyl)2, —SO2C1-4alkyl, —SO2NH2, —SO2NHC1-4alkyl, and —SO2N(C1-4alkyl)2.