Compounds derived from dihydropiridines, pharmaceutical compositions comprising said compounds and method of treatment of muscle disorders comprising administration of said compositions
AssigneeUniversidad De Chile
InventorsMariana Victoria CASAS ATALA, Enrique Zacarías JAIMOVICH PÉREZ
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Abstract
The invention of the present application relates to compounds derived from tetrahydrofuran [3,4-b]pyridine-3-carboxylate, pharmaceutical compositions comprising said compounds and a method of prevention and treatment of muscle disorders comprising administration of said pharmaceutical compositions for recovery of muscular function in a subject in need thereof.
Claims16
A compound having the chemical formula:
- wherein:
- R1 is nitro;
- R2 is hydrogen or alkyl C1-C3;
- R3 is hydrogen or alkyl C1-C3;
- R4 is hydrogen, or
- a pharmaceutically acceptable salt thereof.
A pharmaceutical composition comprising a compound having the chemical formula:
- wherein:
- R1 is nitro;
- R2 is hydrogen or alkyl C1-C3;
- R3 is hydrogen or alkyl C1-C3;
- R4 is hydrogen, or
- a pharmaceutically acceptable salt thereof;
- wherein said pharmaceutical composition further comprises at least one pharmaceutically acceptable carrier.
A pharmaceutical composition for prevention or treatment of a muscle disorder in a subject in need thereof comprising a compound having the chemical formula:
- wherein:
- R1 is nitro;
- R2 is hydrogen or alkyl C1-C3;
- R3 is hydrogen or alkyl C1-C3;
- R4 is hydrogen, or
- a pharmaceutically acceptable salt thereof;
- wherein said pharmaceutical composition further comprises at least one pharmaceutically acceptable carrier.
A method for prevention or treatment of a muscle disorder, comprising administering a therapeutically effective amount of a pharmaceutical composition comprising a compound having the chemical formula:
- wherein:
- R1 is nitro;
- R2 is hydrogen or alkyl C1-C3;
- R3 is hydrogen or alkyl C1-C3;
- R4 is hydrogen, or
- a pharmaceutically acceptable salt thereof;
- wherein said pharmaceutical composition further comprises at least one pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.