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US 2026/0217710 A1Published application
Compositions and methods for modulating hair growth
AssigneesThe Regents of the University of California, Pelage Pharmaceuticals, Inc.
InventorsDaniel L. Sun, Michael E. Jung, Daniel W. Gil
Life of this patent
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Abstract
The present disclosure relates to novel compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
Claims18
1-71. (canceled)
A method of growing hair, comprising:
- administering a compound to a mammal in need of hair growth, wherein the compound is represented by a formula:
- or a pharmaceutically acceptable salt thereof;
- wherein R1 is —, —S(═O)2—, an optionally substituted C1-12 hydrocarbon group or an optionally substituted heterocycle;
- R2 is H, an optionally substituted C1-6 alkyl, an optionally substituted carbocycle, or an optionally substituted heterocycle;
- Y is —,
- and
- R6 is:
4 more elements
Dependencies are inferred from the claim text.