Berberine tauroursodeoxycholate compositions and methods thereof
OwnerLiping Liu, Ru Bai +3inventors
InventorsLiping Liu, Ru Bai, Xinxiang Fu, Junwei Cheng, Mingzheng Xie
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Abstract
The invention provides berberine tauroursodeoxycholate (BTUDC), pharmaceutical compositions and methods of use thereof for the treatment, reduction and/or prevention of Parkinson's disease, or an associated disease and disorder, as monotherapy or in combination with other agents or as an adjuvant. The invention further provides pharmaceutical compositions and methods of use of berberine (BBR) and tauroursodeoxycholic acid (TUDCA) for the treatment, reduction and/or prevention of Parkinson's disease, or an associated disease and disorder, as monotherapy or in combination with other agents or as an adjuvant.
Claims21
A salt having Formula (I):
A salt in substantially pure form, wherein the salt is represented by Formula (I):
A solid form of a compound of Formula (I), which is Form Å, wherein X-ray powder diffraction (XRPD) pattern thereof comprises one or more characteristic diffraction peaks at the following 2θ angles:
- 4.62°, 9.32°,17.02°±0.2°, with a radiation source of Cu-Kα.
21-51. (canceled)
Dependencies are inferred from the claim text.