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US 2026/0217685 A1Published application
Deuterated compounds
AssigneeSun Pharmaceutical Industries Limited
InventorsBrett D. GROTBECK, Jenisha GANDHI, Nancy DEGRACE, Patrick BAZINET
Life of this patent
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Abstract
The present disclosure is directed to deuterated compounds of the general formula: and pharmaceutically acceptable salts thereof. Also disclosed herein are pharmaceutical compositions comprising the deuterated compound.
Claims27
A compound represented by Formula (I)
- or a pharmaceutically acceptable salt thereof, wherein
- Y1 is selected from hydrogen and deuterium;
- each Y2 is independently selected from hydrogen and deuterium;
- and
- each Y3 is independently selected from hydrogen and deuterium;
- provided that at least one of Y1, Y2, and Y3 is deuterium;
- and
- wherein each position designated specifically as deuterium has at least 95% deuterium incorporation.
5 more elements
A pharmaceutical composition comprising a compound represented by the following structural formula:
- or a pharmaceutically acceptable salt thereof,
- wherein Y1 is selected from hydrogen and deuterium;
- each Y2 is independently selected from hydrogen and deuterium, wherein each Y2 is the same;
- each Y3 is independently selected from hydrogen and deuterium, wherein each Y3 is the same;
- provided that at least one of Y2 and Y3 is deuterium;
- and
- wherein each position designated specifically as deuterium has at least 95% deuterium incorporation;
- and a pharmaceutically acceptable carrier.
5 more elements
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25-27. (canceled)
29-34. (canceled)
Dependencies are inferred from the claim text.