Printers for manufacturing constructs for regenerative medicine
OwnerAli TAMAYOL, Mohamadmahdi SAMANDARI +3inventors
InventorsAli TAMAYOL, Mohamadmahdi SAMANDARI, Farnoosh SAEEDINEJAD, Jacob P. QUINT, Amir SEYEDSALEHI
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Abstract
Disclosed herein is a printer for manufacturing a construct for use as a prosthetic, the printer comprising a housing; a piston that is operative to reciprocate in the housing to extrude a volume of a hydrogel; and a stage comprising a porous screen and an inlet port disposed downstream of the housing; where the inlet port is operative to introduce air into the hydrogel; and where the porous screen is operative to reduce air bubble sizes in the hydrogel.
Claims19
A printer for manufacturing a construct for use as a prosthetic, the printer comprising:
- a housing;
- a piston that is operative to reciprocate in the housing to extrude a volume of a hydrogel;
- and
- a stage comprising a porous screen and an inlet port disposed downstream of the housing;
- where the inlet port is operative to introduce air into the hydrogel;
- and where the porous screen is operative to reduce air bubble sizes in the hydrogel.
A printer for manufacturing a construct for use as a prosthetic, the printer comprising:
- a first syringe;
- a second syringe;
- a three-way valve in fluid communication with and located downstream of the first syringe and the second syringe;
- and
- a porous screen located in the three-way valve in a fluid pathway between the first syringe and the second syringe;
- where the mesh is operative to reduce a size of air bubbles contained in a hydrogel or a bioink that is ejected from the first syringe into the second syringe.
A method of manufacturing a construct, the method comprising:
- blending a hydrogel with air to form an aerated hydrogel;
- transmitting the aerated hydrogel through a plurality of porous screens to form a foam;
- disposing the foam on a substrate;
- and
- curing the foam with thermal energy or electromagnetic radiation to form the construct.
Dependencies are inferred from the claim text.