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US 2026/0216306 A1Published application
Dendritic cell-based vaccines and uses thereof
AssigneesMayo Foundation for Medical Education and Research, BioVentures, LLC
InventorsKeith L. Knutson, Matthew S. Block, Allan B. Dietz, Michael P. Gustafson, Martin John Cannon
Life of this patent
Estimating the term…
Abstract
Methods and materials for treating cancer (e.g., ovarian cancer) using a combination of a Th17 DC vaccine, optionally in combination with an immune checkpoint inhibitor, are provided herein.
Claims13
A method for treating a mammal having cancer, wherein said method comprises:
- (a) administering, to said mammal, an effective amount of a vaccine composition capable of activating T cells within said mammal to form activated IL-17-secreting T cells that can recognize one or more antigens expressed by said cancer, and
- (b) administering, to said mammal, an effective amount of an immune checkpoint inhibitor (ICI).
Dependencies are inferred from the claim text.