Compositions and methods for modulating inflammatory response
AssigneeTurtle Bear Holdings, LLC
InventorPaul E. STAMETS
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Abstract
Described herein are mushroom compositions and methods for treating, prophylaxis of, or ameliorating symptoms of one or more adverse reactions triggered by an infectious disease or condition that increases an anti-inflammatory response in a subject with such compositions. In one aspect the composition comprises an aqueous or solid fraction of a mycelium, a fermented substrate thereof, or a combination thereof optionally combined with one or more buffering agents, ethanol, and water.
Claims79
A composition for treating, prophylaxis of, or ameliorating symptoms of one or more adverse reactions triggered by an infectious disease or condition that increases an anti-inflammatory response in a subject, the composition comprising:
- an aqueous or solid fraction of a mycelium, a fermented substrate thereof, or a combination thereof;
- one or more buffering agents;
- ethanol;
- and
- water.
A composition for treating, prophylaxis of, or ameliorating symptoms of one or more adverse reactions triggered by an infectious disease or condition that increases an anti-inflammatory response in a subject, the composition comprising:
- an aqueous or solid fraction of Fomitopsis officinalis mycelium, a fermented substrate thereof, or a combination thereof;
- one or more buffering agents;
- ethanol;
- and
- water.
A composition comprising an aqueous or ethanolic extract of Fomitopsis officinalis mycelium.
Use of the composition of any one of the preceding claims for modulating an inflammatory response comprising administering an effective amount of the composition to a subject in need thereof.
A means for modulating an inflammatory response comprising administering to a subject in need thereof an effective amount of the composition of any one of the preceding claims.
A method for treating, prophylaxis of, or ameliorating symptoms of an infectious disease comprising:
- administering to a subject in need thereof an effective amount of a composition comprising:
- an aqueous or solid fraction of a mycelium, a fermented substrate thereof, or a combination thereof;
- one or more buffering agents;
- ethanol;
- and
- water.
A method for treating, prophylaxis of, or ameliorating symptoms of a bacterial or viral infection comprising administering an effective amount of an aqueous or solid extract of one or more of Fomitopsis officinalis, Trametes versicolor, Hericium erinaceus, or Inonotus obliquus.
A method for modulating an inflammatory response associated with a bacterial or viral infection comprising administering an effective amount of an aqueous or solid extract of one or more of Fomitopsis officinalis, Trametes versicolor, Hericium erinaceus, or Inonotus obliquus.
A method of manufacturing the composition of any one of the preceding claims, the method comprising:
- growing a mushroom on a substrate;
- and,
- separating the mushroom mycelium from a fruitbody and the substrate.
A method for treating or lessening the severity of any type of pain in a subject in need thereof comprising:
- administering to the subject an effective amount of a composition comprising:
- an aqueous or solid fraction of a mycelium, a fermented substrate thereof, or a combination thereof;
- one or more buffering agents;
- ethanol;
- and
- water.
A method for enhancing a viral therapy comprising:
- administering to a subject an effective amount of a composition comprising:
- an aqueous or solid fraction of a mycelium, a fermented substrate thereof, or a combination thereof;
- one or more buffering agents;
- ethanol;
- and
- water.
Dependencies are inferred from the claim text.