Imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrazine derivatives as mllt1 and mllt3 inhibitors

A compound of formula (I):

• wherein:
• one of Z2 and Z4 is N and the other is C, Z1 is N or —C(R4)—, Z3 is —C(R4)—, Y1 is N or —C(R7)—, Y2 is N or —C(R6)—, and Y3 is N or —C(R5)—;
• Hy is a 4- to 7-membered heterocyclyl ring containing X and at least one N atom, wherein:
• ring Hy is linked to ring A via a C atom within ring Hy, said C atom also being linked to R2;
• a N atom within ring Hy is substituted by R1;
• X is a bond, —N(R11)—, O, S, —S(O)2—, —S(O)(NR11)—, or —C(R11)2—;
• and the rest of ring Hy is unsubstituted or substituted by one or two R3;
• L is —C(O)N(H)—, wherein either (i) the C atom of L is bonded to R8, and the N atom of L is bonded to ring B;
• or (ii) the C atom of L is bonded to ring B, and the N atom of L is bonded to R8;
• R1 is H, C1-4 cycloalkyl, or C1-4 alkyl which is itself unsubstituted or substituted with one C1-4 alkoxy or one, two or three halo;
• R2 is H or methyl;
• each R3 is independently selected from C1-4 alkyl, C1-4 alkoxy, phenyl, a 5- to 6-membered heteroaryl ring and halo, or (i) two R3 linked to adjacent C atoms in ring Hy form, together with the C atoms to which they are attached, a C5-6 cycloalkyl ring, or (ii) two R3 linked to the same C atom in ring Hy form, together with the C atom to which they are attached, a C3-6 cycloalkyl ring or a C3-6 heterocycloalkyl ring;
• R4, R6, and R7 are independently selected from H, halo, C1-4 alkoxy, and C1-4 alkyl which is itself unsubstituted or substituted by one, two or three halo;
• R5 is selected from H, halo, C1-4 alkoxy, C3-5 cycloalkyl and C1-4 alkyl which is itself unsubstituted or substituted by one, two or three halo;
• R8 is a group selected from a 6- to 10-membered aryl ring, a 5- to 10-membered heteroaryl ring, a 5- to 10-membered heterocyclyl ring, and a 5- to 6-membered cycloalkyl ring, the group R8 being unsubstituted or substituted by one, two or three substituents independently selected from halo, C1-4 alkoxy, R10, —(C1-4 alkylene)-R10, ═O, —CN, and C1-4 alkyl which is itself unsubstituted or substituted by one or two R9;
• each R9 is independently selected from halo and C1-4 alkoxy;
• R10 is a group selected from a 5- to 6-membered heteroaryl ring, a 3- to 6-membered cycloalkyl ring, a 4- to 6-membered heterocyclyl ring, and a phenyl ring, the group R10 being unsubstituted or substituted by one or two substituents independently selected from C1-4 alkyl, C1-4 alkoxy, and halo;
• each R11 is independently selected from H, C1-4 alkyl, and C1-4 cycloalkyl;
• or a pharmaceutically acceptable salt thereof.