Polymersomes for delivery of nucleic acid cargoes

Abstract

The present invention relates to the field of polymersomes for the effective delivery of nucleic acid cargoes to target cells within the body. Specifically, the present invention is directed to a cargo-containing polymersome which comprises (a) a polymersome and (b) a cargo encapsulated within the polymersome, wherein said cargo comprises a nucleic acid and a nucleic acid-binding protein. The present invention is further directed to pharmaceutical compositions comprising a plurality of such polymersomes and one or more pharmaceutically acceptable excipients or diluents. The present invention is further directed to uses of such polymersomes and pharmaceutical compositions in medicine, and to vaccines comprising such polymersomes.

Dependencies are inferred from the claim text.