Cosmetic composition for enhancing resistance to aging

A cosmetic composition comprising:

• a. a blend of skin actives comprising blueberry extract;
• pomegranate extract;
• dipotassium glycyrrhizate;
• and hydroxypropyl tetrahydropyrantriol;
• and
• b. a cosmetic carrier system comprising:
• i. water;
• ii. at least one silicone-based emulsifier;
• iii. at least one silicone oil;
• iv. at least one branched, liquid alkane;
• and
• v. at least one hydrating agent,
• wherein the cosmetic composition confers a statistically significant reduction in the expression of at least one gene selected from the group consisting of mitogen-activated protein kinase 5 [MAP3K5], Intraflagellar transport protein 57 [IFT57], Multifunctional ROCO Family Signaling Regulator 1 [MFHAS11, and combinations thereof.

A cosmetic composition comprising a gel-cream emulsion comprising:

• a. a blend of skin actives comprising blueberry extract;
• pomegranate extract;
• dipotassium glycyrrhizate;
• and hydroxypropyl tetrahydropyrantriol, wherein blueberry extract in the form of Vaccinium myrtillus fruit extract is present in a range in a range from about 0.01% to about 5%, pomegranate extract in the form of Punica granatum fruit extract is present in a range in a range from about 0.01% to about 5%, dipotassium glycyrrhizate is present in a range in a range from about 0.05% to about 5%, and hydroxypropyl tetrahydropyrantriol is present in a range in a range from about 5% to about 15%;
• and
• b. a cosmetic carrier system comprising:
• i. water present in a range from about 30% to about 40%;
• ii. at least one silicone-based emulsifier comprising dimethicone/PEG-10/15 crosspolymer and lauryl PEG-9 polydimethylsiloxyethyl dimethicone, the dimethicone/PEG-10/15 crosspolymer present in a range in a range from about 3% to about 4%, the lauryl PEG-9 polydimethylsiloxyethyl dimethicone present in a range in a range from about 1% to about 1.5%;
• iii. at least one silicone oil comprising dimethicone present in a range in a range from about 5% to about 25%;
• iv. at least one branched, liquid alkane comprising isohexadecane present in a range in a range from about 1% to about 15%;
• v. at least one hydrating agent present in a range from about 5% to about 30% and comprising glycerin, propylene glycol, ethylhexyl hydroxystearate, and synthetic wax;
• and
• vi. at least one additive comprising aluminum starch octenylsuccinate, bismuth oxychloride, cellulose, silica silylate, phenoxyethanol, sorbitol, sodium citrate, magnesium sulfate, and trisodium ethylenediamine disuccinate,
• all amounts by weight, based on the weight of the composition,
• wherein the cosmetic composition confers a statistically significant reduction in the expression of at least one gene selected from the group consisting of mitogen-activated protein kinase 5 [MAP3K5], Intraflagellar transport protein 57 [IFT57], Multifunctional ROCO Family Signaling Regulator 1 [MFHAS11, and combinations thereof, and wherein the cosmetic composition is intended to leave on, rinse off, or use as a cleanser.