Balloon expandable stent with symmetrical crimped configuration for transcatheter implantation of a cardiac valve prosthesis

A transcatheter valve prosthesis comprising:

• a stent having a crimped configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve, the stent including:
• an inflow portion formed proximate to an inflow end of the stent, the inflow portion including a plurality of crowns and a plurality of struts with each crown being formed between a pair of opposing struts, a plurality of side openings being defined by the plurality of crowns and the plurality of struts,
• an outflow portion formed proximate to an outflow end of the stent, the outflow portion including a plurality of crowns and a plurality of struts with each crown being formed between a pair of opposing struts, wherein endmost outflow crowns are formed at the outflow end of the stent, and
• a plurality of axial frame members extending between the inflow portion and the outflow portion, each axial frame member extending in an axial direction along a longitudinal axis of the stent from a crown of the inflow portion to at least a crown of the outflow portion, each axial frame member having a first end directly adjacent to a crown of the inflow portion, wherein a pair of cutouts are disposed on opposing sides of the first end of each axial frame member at an area of transition between the crown of the inflow portion and the axial frame member, each cutout having a length between 1% and 20% of the length of the axial frame member between the first end and the crown of the outflow portion;
• and
• a prosthetic valve disposed within and secured to one or more axial frame members of the plurality of axial frame members of the stent, the prosthetic valve being configured to block blood flow in one direction to regulate blood flow through a central lumen of the stent.

A transcatheter valve prosthesis comprising:

• a stent having a crimped configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve, the stent including:
• a plurality of axial frame members, wherein the plurality of axial frame members includes a plurality of commissure posts and a plurality of axial struts, each axial strut being disposed between a pair of commissure posts,
• an inflow portion including at least three rows of struts and crowns formed between adjacent pairs of the struts, wherein the at least three rows of the inflow portion are formed between an inflow end of the axial frame members and an inflow end of the stent, and
• an outflow portion formed proximate to the stent and including a single row of struts and crowns formed between adjacent pair of the struts, the outflow portion being coupled to an outflow end of the axial frame members, wherein exactly two struts of the plurality of struts of the outflow portion are disposed between adjacent axial frame members,
• wherein each axial frame member extends in an axial direction along a longitudinal axis of the stent from a crown of the inflow portion to at least a crown of the outflow portion, each axial frame member having a first end directly adjacent to a crown of the inflow portion, wherein a pair of cutouts are disposed on opposing sides of the first end of each axial frame member at an area of transition between the crown of the inflow portion and the axial frame member, each cutout having a length between 1% and 20% of the length of the axial frame member between the first end and the crown of the outflow portion,
• a prosthetic valve disposed within and secured to the plurality of commissure posts of the stent, the prosthetic valve being configured to block blood flow in one direction to regulate blood flow through a central lumen of the stent.