System, method and computer-accessible medium for effectuating real time image-based physiology and/or coronary measurements

A method of performing image-based coronary assessments within a body, comprising:

• disposing at least one reference object within an imaging field-of-view of an X-ray radiation generator, and in vicinity of at least one portion of a body or a target object;
• providing an X-ray radiation to at least one portion of a body or a target and the at least one reference object;
• and
• generating at least one X-ray image of the at least one portion containing an image of the reference object based on (i) a first radiation provided from the at least one portion, and (ii) a second radiation provided from the reference object.

A method of performing real-time image-based coronary assessment, comprising:

• providing an X-ray radiation to at least one portion of a body
• generating at least one X-ray image of the at least one portion after a partially radiopaque contrast agent is provided in or on the at least one portion;
• transmitting the X-ray image directly to a processor;
• measuring a physiology index based on the X-ray image;
• and displaying a representation of the physiology index on a display.

A method for providing a real-time image-based coronary assessment, comprising:

• providing an X-ray radiation to at least one portion of a body by an X-ray apparatus;
• generating at least one X-ray image of the at least one portion after at least partially radiopaque contrast agent is provided into the at least one portion;
• and
• with a computer processor, (i) receiving the X-ray image directly from the X-ray apparatus, and (ii) extracting information from the directly-obtained X-ray image.

A measurement system, comprising:

• at least one partially radiopaque reference object provided within an imaging field-of-view of an X-ray radiation source and in vicinity of at least one portion of a body or a target object, and configured to receive the X-ray radiation;
• a data interface;
• and
• at least one computer processor configured to:
• receive, directly via the data interface, at least one X-ray image of vasculature of the at least one portion of the body containing at least part of an image of the reference object;
• calibrate the dimensions of the at least one X-ray image based on the reference object.

An imaging system, comprising:

• at least one insertion device structured to be provided into a body and including at least one section which is configured to receive the X-ray radiation;
• and
• at least one computer processor configured to generate an X-ray image of vasculature of the at least one portion of the body containing an image of at least one portion of the body based on (i) a second radiation provided from the at least one section;
• and (ii) information regarding the at least one insertion device.