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US 2026/0215432 A1Published application
Antimicrobial conjugated oligoelectrolytes and methods thereof
AssigneeNational University of Singapore
InventorsGuillermo BAZAN, Kaixi ZHANG, Jun Wei Samuel CHAN
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Abstract
The present disclosure relates, in general terms, to conjugated oligoelectrolytes which are antimicrobial and their methods of use thereof. The compounds may be used to treat a bacterial infection or disease.
Claims22
A compound of Formula (I) or a pharmaceutically acceptable salt, solvate or isomer thereof:
- wherein
- each R1, R2 and R3 are independently selected from H, optionally substituted alkyl, optionally substituted alkoxy;
- wherein at least one of R1, R2 and R3 on each phenylene ring is
- wherein each R4 is independently selected from optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocyclyl, optionally substituted cycloalkyl, and optionally substituted cycloalkenyl;
- n is an integer selected from 2 to 10;
- and
- X is a linker configured to maintain the π-π conjugation between the two phenylene rings.
4 more elements
9-15. (canceled)
21-22. (canceled)
Dependencies are inferred from the claim text.