Organic Electrolyte-Gated Field Effect Transistor Biosensor

An organic electrolyte-gated field effect transistor biosensor comprising:

• a gate electrode;
• a source electrode;
• a drain electrode;
• a semiconductor material in electrical contact with the source electrode and the drain electrode;
• and
• a microfluidic channel structure comprising at least one thermoplastic dielectric material and at least one interior surface bearing a biorecognition entity, wherein the at least one interior surface is separated from the gate electrode, the source electrode, the drain electrode and the semiconductor material by the thermoplastic dielectric material and wherein the thermoplastic dielectric material comprises one or more materials selected from the group consisting of polylactic acid (PLA), polycaprolactone (PCL), poly(ethyl methacrylate) (PEMA), polybutylene terephthalate (PBT), polyethylene terephthalate (PET), polyethylene (PE), polypropylene (PP), polystyrene (PS), polytetrafluoroethylene (PTFE), cellulose, acylated cellulose derivatives, cellulose acetate, cellulose acetate butyrate, cellulose propionate, acrylonitrile butadiene styrene (ABS), acrylonitrile styrene acrylate (ASA), polycaprolactam (PC), polybutadiene (PBD), polydimethylsiloxane (PDMS) and nylon polyamides.