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US 2026/0209691 A1Published application
Method and composition for reprogramming cells
AssigneeAthergen, Inc.
InventorJoseph Chalifoux
Life of this patent
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Abstract
A cell reprogramming composition and method wherein the composition includes a base molecule, β-nicotinamide mononucleotide, trichostatin A and zwitterionic liposomes and wherein the method includes receiving a cell and reprogramming agents, wherein the reprogramming agents comprise Oct-4, Sox 2 and Klf4, to reprogram the cell to an embryonic state.
Claims19
1-10. (canceled)
A method, the method comprising:
- receiving a cell;
- and
- receiving a composition, the composition comprising:
- a base molecule;
- a combination of β-nicotinamide mononucleotide and leucomethylene blue, wherein the combination comprises aqueous leucomethylene blue β-nicotinamide mononucleotide version 1 (AqLNMNo1);
- a combination of trichostatin A and aqueous leucomethylene blue β-nicotinamide mononucleotide version 1, wherein the combination comprises aqueous leucomethylene blue β-nicotinamide mononucleotide version 2 (AqLNMNo2);
- and
- zwitterionic liposomes;
- and
- attaching reprogramming agents to the composition, wherein the reprogramming agents comprise Oct-4, Sox 2 and Klf4.
7 more elements
The method of claim 1, wherein the zwitterionic liposomes are hydrated and extruded.
Dependencies are inferred from the claim text.