Affibody binding specifically to cd137 and use thereof
AssigneeAbclon Inc.
InventorsHyun-Jong LEE, Sang-Ho AHN, Jong-Ho LEE, Jong-Seo LEE
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AssigneeAbclon Inc.
InventorsHyun-Jong LEE, Sang-Ho AHN, Jong-Ho LEE, Jong-Seo LEE
Estimating the term…
The present invention relates to: an affibody binding specifically to the extracellular domain of CD137; a protein complex comprising the described affibody and an antibody that binds specifically to a protein on the surface of cancer cells or an antigen-binding fragment thereof; and a pharmaceutical composition for preventing or treating cancer, comprising same as an active ingredient. By using the affibody binding specifically to CD137, a protein complex binding specifically to T cells and, simultaneously, binding specifically to an antigen on the surface of various types of cancer cells can be developed and effectively used in the prevention or treatment of blood cancer and solid cancer.
An affibody, comprising an amino acid sequence represented by any one of SEQ ID NOS:
-9. (canceled)
(canceled)
The method of claim 8, wherein the cancer is a hematologic cancer or a solid tumor.
Dependencies are inferred from the claim text.