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US 2026/0209170 A1Published application
Methods of synthesizing 4-valyloxybutyric acid
AssigneeXwpharma Ltd.
InventorsJia-Ning XIANG, Hao-Wei SHIH, Xiaoming WU, Xuan ZHANG, James TIEN
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Abstract
The present disclosure is directed synthetic methods for the preparation of 4-valyloxybutyric acid. The synthetic methods described herein employ a diverse array of protecting group strategies and reaction conditions. Additionally, the present disclosure is directed to compounds useful as synthetic intermediates in the preparation of 4-valyloxybutyric acid.
Claims6
A compound having the structure of Formula (I-B):
- wherein, R1 is selected from hydrogen and —C(═O)CH2(C6-15 carbocycle), wherein the C6-15 carbocycle is optionally substituted with one or more substituents selected from C1-6 alkyl, halogen, hydroxy, alkoxy, and amino.
Dependencies are inferred from the claim text.