Heat treatment means for printing device of an enzymatic synthesis apparatus
AssigneeDNA Script
InventorsAdrian HORGAN, Damiano VERARDO
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Abstract
The present invention relates to a printing device (1) configured for the enzymatic synthesis of biomolecules, comprising a printing head (2), at least one ink reservoir (7) containing synthesis reagents and a substrate plate (16) configured to receive ink drops (6), the printing device (1) being equipped with heat treatment means (26) configured to generate a positive temperature differential between the print head (2) and/ or the ink reservoir (7) on the one hand and the substrate plate (16) on the other.
Claims16
A printing device configured for the enzymatic synthesis of biomolecules, comprising
- a print head,
- at least one ink reservoir containing synthesis reagents, and
- a substrate plate configured to receive ink drops,
- wherein the printing device comprises at least one of a heater and a cooler configured to generate a temperature differential between the substrate plate and at least one of the print head and the ink reservoir,
- wherein the temperature differential is at least 10° C., and wherein the temperature of the substrate plate is higher than the temperature of the at least one of the print head and the ink reservoir.
A method for performing enzymatic synthesis of biomolecules with a printing device, wherein the printing device comprises an ink reservoir, a print head, and a substrate plate, the method comprising:
- providing ink to the ink reservoir, wherein the ink comprises synthesis reagents,
- generating a temperature differential between the substrate plate and at least one of the ink reservoir and the print head, wherein the temperature differential is at least 10° C., and wherein a first temperature measured at the at least one of the ink reservoir and the print head is between 0 and 25° C., and a second temperature measured at the substrate plate is between 25° C. and 60° C.,
- generating a plurality of ink droplets at the print head, wherein the print head is connected to the ink reservoir, and
- depositing the plurality of ink droplets onto the substrate plate.
Dependencies are inferred from the claim text.