Blood Plasma Product
AssigneeVelico Medical, Inc.
InventorsQiyong Peter Liu, Herman E Snyder, Evan P. Ordway, William J. Merritt, Robert R. Andrews, Clair Strohl, Jihae Sohn, Lisa A. Buckley, Mark A. Popovsky
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AssigneeVelico Medical, Inc.
InventorsQiyong Peter Liu, Herman E Snyder, Evan P. Ordway, William J. Merritt, Robert R. Andrews, Clair Strohl, Jihae Sohn, Lisa A. Buckley, Mark A. Popovsky
Estimating the term…
The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A).
1) A reconstituted previously spray dried plasma made from rehydrating a spray dried plasma with water, wherein the spray dried plasma is made from donor plasma from one or more donors;
14) A reconstituted previously spray dried plasma made from rehydrating a spray dried plasma with water, wherein the spray dried plasma is made from donor plasma from one or more donors;
17) A reconstituted previously spray dried plasma made from rehydrating a spray dried plasma with water, wherein the spray dried plasma is made from donor plasma from one or more donors;
Dependencies are inferred from the claim text.