Biventricular assist system
AssigneesIstanbul Bilgi Universitesi, Koc Universitesi
InventorsIbrahim Basar AKA, Kerem PEKKAN, Canberk YILDIRIM
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Abstract
A biventricular assist system includes a left ventricle assist device and a self-driving integrated aortic turbine ventricle assist device including a blood pump and blood turbine coupled together that can be easily manufactured to patient specifications. A control method using a master/slave approach is provided, wherein said biventricular assist system able to mimic the Frank-Starling mechanism of the heart without need for external sensors or additional mechanisms.
Claims14
A biventricular assist system comprising a left ventricle assist device (LVAD), an integrated aortic turbine ventricle assist device comprising a blood pump and a blood turbine coupled by a shaft, and a control system, wherein
- the LVAD has an inflow conduit configured for receiving blood from a left ventricle of a heart and an outflow conduit configured for returning a fraction of the blood to blood turbine or an aorta and the remaining blood to a systemic circulation, the blood pump has an inflow conduit configured for receiving blood from a right atrium or right ventricle of the heart and an outflow conduit configured for returning blood to a pulmonary circulation, and said the blood turbine has an inflow conduit configured for receiving blood from the LVAD or from the aorta or an artery having a high blood pressure and an outflow conduit configured for returning blood to the systemic circulation,
- the blood turbine is configured to generate power from a kinetic energy of a blood flow from the outflow from the left ventricle assist device and transmit said the power to the blood pump via a rotation of the shaft, wherein said the integrated aortic turbine ventricle assist device is free of an active or external power source to be operable by the blood turbine and
- the control system comprises a left ventricle assist device as a master controller and an integrated aortic turbine ventricle assist device as a slave controller, wherein pump speed of the blood pump is configured to be variable based on a flowrate of the outflow from the left ventricle assist device and wherein the control system is passively configured to ensure that Frank-Starling balance is obtained.
A method for manufacturing a patient-specific integrated aortic turbine ventricle assist device comprising a blood pump and a blood turbine coupled by a shaft comprising steps of:
- (vi) obtaining right heart failure patient-specific hemodynamic parameters,
- (vii) modifying a right heart failure model with the hemodynamic parameters,
- (viii) setting a target for a patient and performing computational analysis,
- (ix) determining the required design parameters for the patient-specific integrated aortic turbine ventricle assist device and
- (x) fabricating a patient specific right ventricle support integrated aortic turbine ventricle assist device by rapid prototyping.
Dependencies are inferred from the claim text.