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US 2026/0207771 A1Published application
Viral vectors with engineered function and methods of production thereof
AssigneeLilium Therapeutics Inc.
InventorJonathan Lipsitz
Life of this patent
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Abstract
Provided herein are viral vectors with engineered function and methods of producing the same.
Claims30
A viral vector core having on its surface a first chemical handle.
A viral vector comprising one or more exogenous targeting protein(s), one or more exogenous immune modifying protein(s), and/or one or more polymer(s) covalently attached to its surface through a conjugation signature.
A method of making a viral vector, wherein the method comprises:
- (a) contacting a viral vector core comprising on its surface a first chemical handle with an exogenous targeting protein, an exogenous immune modifying protein, or a polymer comprising a second chemical handle, and
- (b) covalently conjugating the first chemical handle with the second chemical handle, to produce the viral vector.
Dependencies are inferred from the claim text.