Use of estetrol in hepatically impaired patients
AssigneeEstetra Srl
InventorsMélanie Taziaux, Anne Gallez
Life of this patent
Estimating the term…
Abstract
The present invention relates to a composition comprising an estetrol component for use in alleviating estrogen deficiency symptoms including menopause-associated symptoms in subjects that are characterized by a degree of hepatic impairment. The composition described herein displays favorable pharmacokinetic properties when compared to existing estrogen-based compositions that aim to alleviate estrogen deficiency symptoms. Also described herein are uses related to the above and corresponding methods of treatment.
Claims21
1-16. (canceled)
A method for alleviating estrogen deficiency symptoms in a hepatically impaired subject, comprising orally administering a composition formulated as an oral dosage unit to a hepatically impaired subject, wherein said composition comprises an estetrol component and is administered at a daily dose equivalent to from about 15 mg to about 25 mg of estetrol.
Dependencies are inferred from the claim text.