Pharmaceutical composition comprising lurbinectedin, preparation method therefor, and use thereof

Abstract

A pharmaceutical composition comprising lurbinectedin, a preparation method therefor, and use thereof. The pharmaceutical composition comprising lurbinectedin is a freeze-dried composition comprising lurbinectedin, a buffer derived from an inorganic acid, and a proppant. Lurbinectedin, the active ingredient of the pharmaceutical composition, can be completely dissolved and can ensure that the pH value of the pharmaceutical composition is stable during storage without influencing the quality and stability of the active pharmaceutical ingredient, featuring a low impurity level and long-term preservation potential, and thereby demonstrating significant application prospects in treating cancer and associated diseases. The preparation method for the pharmaceutical composition is simple and convenient to operate and cost-effective for production, facilitating large-scale production and contributing to the widespread use of pharmaceutical formulations.

Dependencies are inferred from the claim text.