Taste Masking Composition and Process

Abstract

The invention is directed to a taste-masked pharmaceutical composition dosage form that includes a core comprising a pharmaceutically active ingredient and one or more pharmaceutically acceptable excipients, a seal coating encasing the core and a taste masking coating encasing the seal coated core. The taste masking coating includes a polymer that is insoluble at a pH above 5 and soluble below a pH of 5, an optional plasticizer and an anti-tacking agent present in an amount of between 70-140% w/w of the polymer. In a process for forming the coated core, the taste masking coating is applied to the seal coated core at a spray rate of 2.3-3.6 grams/min/kg and heating is applied in the coating apparatus such that an exhaust temperature of 36-40° C. from the coating apparatus is attained.

Dependencies are inferred from the claim text.