Nutritional compositions for use in glycogen storage disease
AssigneeN.V. Nutricia
InventorsJanna Willemina Woestenenk, Leonardo Cornacchia, Evan Abrahamse, Bartholomeus Theodorus Gerardus Kompier, Simon David Anders
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Abstract
The invention relates a nutritional compositions comprising lipid, OSA starch, protein, an encapsulating agent and carbohydrates, wherein the composition comprises lipid-containing particles which have a lipid core and wherein said lipid core is coated with OSA starch, and wherein the lipid core and OSA starch coating comprise less than 4 wt % protein altogether and relates to the method of making the nutritional compositions and further relates to the nutritional composition for use in glycogen storage disease.
Claims15
A method for manufacturing a nutritional composition comprising lipid, octenyl succinyl anhydride substituted starch (OSA starch), protein, an encapsulating agent and digestible carbohydrates, the method comprising:
- (a) emulsifying lipid with a first aqueous phase and OSA starch, wherein preferably the dry weight ratio of OSA starch to lipid is in the range from 1:3 to 1:5, to obtain an emulsified O/W composition;
- (b) homogenising protein, water and optionally other water-soluble components, to obtain a second aqueous phase;
- (c) combining the emulsified O/W composition from step (a) with the second aqueous phase from step (b), to obtain a mixture and optionally adding further ingredients to the mixture;
- (d) optionally pasteurizing the mixture provided in step (c);
- (e) spray-drying the mixture obtained in step (c) or step (d) to provide a spray-dried composition;
- (f) dry-blending digestible carbohydrates into the spray-dried composition;
- wherein less than 4 wt % protein based on total protein weight in the nutritional composition is present in the emulsified O/W composition of step (a) and wherein the encapsulating agent is added prior to spray-drying in step (e).
A nutritional composition comprising lipid, OSA starch, protein, an encapsulating agent and digestible carbohydrates, wherein the composition comprises lipid-containing particles which have a lipid core and wherein said lipid core is coated with OSA starch, and wherein the lipid core and OSA starch coating comprise less than 4 wt % protein altogether, based on total protein weight in the nutritional composition, and wherein the OSA starch coating is coated with an adjacent, second layer comprising protein, and wherein the encapsulating agent can be present in said second layer and/or the encapsulating agent can be coating said second layer, and wherein the composition comprises 1-14 wt % OSA starch based on total dry weight of the composition.
Dependencies are inferred from the claim text.