Method for gene regulation and use thereof
AssigneePeking University
InventorsXuefei HU, Yi RAO
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Abstract
Provided is a method for preparing a non-human animal with GIGYF1 gene deletion. The non-human animal can be used to screen the use of a recombinant nucleic acid in treating specific diseases. Specifically, also provided is use of the recombinant nucleic acid in treating metabolic diseases and/or symptoms.
Claims17
A method for alleviating, preventing and/or treating a specific disease and/or symptom, comprising administration of a formulation for interfering with GIGYF1, GIGYF1 variants, truncated versions and analogs thereof.
A cell comprising a formulation for interfering with GIGYF1, GIGYF1 variants, truncates and analogs thereof.
A modified non-human animal, wherein the expression level of GIGYF1 gene of the modified non-human animal is reduced compared with a wild-type non-human animal.
Dependencies are inferred from the claim text.