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US 2026/0200978 A1Published application
Peptide inhibitors of beta-lactamase
AssigneeThe Curators of the University of Missouri
InventorsHongmin SUN, Xiaoqin ZOU, Xiao HENG, Xianjin XU
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Abstract
Disclosed herein are new peptide inhibitors of beta-lactamase that can improve the efficacy of currently available antibiotics. Methods of using the peptide inhibitors for treating bacterial infections are also disclosed.
Claims23
An antibacterial peptide comprising a binding motif that comprises an amino acid sequence selected from the group consisting of:
- dGdTdAdAdAdQdAdLdYdTdK (SEQ ID NO:1),
- dGdTdAdAdAdQdAdLdYdTdKdLdYdKdLdIdKdKdFdLdKdK (SEQ ID NO:2), and
- combinations thereof.
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Dependencies are inferred from the claim text.