US 2026/0200882 A1 · NOVEL FIVE-MEMBERED HETEROCYCLE SUBSTITUTED STYRENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF

Abstract

The present application relates to the technical field of biological medicines, and in particular relates to a novel five-membered heterocycle substituted styrene derivative, and a preparation method therefor and the use thereof. The styrene derivative has a novel structure and a significant anti-inflammatory effect. A new treatment method and a new anti-inflammatory drug molecule is provided for solving the problems of a series of adverse reactions, tolerance, side effects, etc., being easily generated due to the long-term use of a large number of anti-inflammatory drugs.

Claims10

Dependent claims

A novel five-membered heterocycle substituted styrene derivative, having a structure shown in formula (I) or a pharmaceutically acceptable salt thereof, a solvent compound of the pharmaceutically acceptable salt, an enantiomer, a diastereoisomer, a tautomer, a racemate or a combination thereof;

wherein in formula (I), R1 and R3 are selected from H, OH, alkoxy or acyl;
R2 is selected from H, alkyl, cycloalkyl, alkenyl, cycloalkenyl, aralkyl or halogen;
X is selected from O, S or NR4, and R4 is selected from H or alkyl;
and Y is selected from C or N.

1 more element

Dependencies are inferred from the claim text.

Novel five-membered heterocycle substituted styrene derivative, and preparation method therefor and use thereof

Life of this patent

Novel five-membered heterocycle substituted styrene derivative, and preparation method therefor and use thereof

Life of this patent

Abstract

Claims10