US 2026/0199896 A1 · Nucleic Acid Amplification Chip, Nucleic Acid Amplification Device, and Nucleic Acid Amplification Method

Abstract

Provided is a nucleic acid amplification chip that enables high-speed movement of a solution more easily without measuring the movement of the solution by fluorescence detection, and suppresses the generation of air bubbles. The nucleic acid amplification chip is provided which includes a flow channel including, between a first connecting tube having a first opening and a second connecting tube having a second opening, a first protruding tube that is protruding in a first direction and communicates with the first connecting tube; a second protruding tube that is protruding in the first direction and communicates with the second connecting tube; and a tubular bridge section that allows fluid communication between the first protruding tube and the second protruding tube.

Claims15

Dependent claims

A nucleic acid amplification chip comprising a flow channel including:

between a first connecting tube having a first opening and a second connecting tube having a second opening,
a first protruding tube that is protruding in a first direction and communicates with the first connecting tube;
a second protruding tube that is protruding in the first direction and communicates with the second connecting tube;
and
a tubular bridge section that allows fluid communication between the first protruding tube and the second protruding tube.

2 more elements

A nucleic acid amplification device comprising:

the nucleic acid amplification chip comprising a flow channel including:
between a first connecting tube having a first opening and a second connecting tube having a second opening,
a first protruding tube that is protruding in a first direction and communicates with the first connecting tube;
a second protruding tube that is protruding in the first direction and communicates with the second connecting tube;
and
a tubular bridge section that allows fluid communication between the first protruding tube and the second protruding tube;
a first heater;
a second heater;
and
a gas transport device, wherein
the first heater heats the first protruding tube at a first temperature,
the second heater heats the second protruding tube at a second temperature that is different from the first temperature, and
the gas transport device transports gas in the flow channel.

10 more elements

Dependencies are inferred from the claim text.

Facts

Application

19/137,581Filed 3 Oct 2023

Priority

JP 2022-20135616 Dec 2022

Published

16 Jul 2026

Term ends

Not estimatedThe source records don’t support an estimate.

Classification14 codes

B01L 3/502715
By integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g.…
B01L 3/50273
By integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g.…
B01L 3/502784
Characterised by multiphase flow arrangements: specially adapted for droplet or plug flow, e.g. digital microfluidics
B01L 7/525
With provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples: with physical…

Nucleic Acid Amplification Chip, Nucleic Acid Amplification Device, and Nucleic Acid Amplification Method

Life of this patent

Nucleic Acid Amplification Chip, Nucleic Acid Amplification Device, and Nucleic Acid Amplification Method

Life of this patent

Abstract

Claims15