US 2026/0199680 A1 · MONITORING A QUALITY OF NEURAL RECORDINGS

Abstract

Automated assessment of neural response recordings involves storing a set of basis functions comprising at least one compound action potential basis function and at least one artefact basis function. Neural recordings of electrical activity in neural tissue are obtained by application of stimuli, using a single configuration of stimulation and recording. Each neural recording is decomposed by determining at least one parameter which estimates at least one of a compound action potential and an artefact. The at least one parameter is/are determined for each respective one of the plurality of neural recordings, to yield a plurality of values. A spread of the plurality of values is determined. An indication that the neural response recordings are of higher quality is output if the spread is small. An indication that the neural response recordings are of lower quality is output if the spread is large.

Claims21

Dependent claims

A system for automated assessment of a configuration of neural stimulation and recording, the system comprising:

an implantable stimulation device configured to apply a plurality of stimuli to neural tissue;
an input for receiving a plurality of neural recordings of electrical activity in the neural tissue, the neural recordings being captured by the implantable stimulation device subsequent to respective stimuli applied to the neural tissue using the configuration of stimulation and recording, the configuration comprising a stimulation electrode and a recording electrode;
and
a processor configured to:
repeatedly determine a plurality of values of a parameter which characterizes a compound action potential in each one of the plurality of neural recordings;
determine an indication of the quality of the configuration of stimulation and recording as a quality of a growth curve that would be fitted to the plurality of values of the parameter;
and
use the configuration of stimulation and recording for ongoing therapy based on the indication of quality.

5 more elements

Dependencies are inferred from the claim text.

Monitoring a quality of neural recordings

Life of this patent

Monitoring a quality of neural recordings

Life of this patent

Abstract

Claims21