Multi-use peritoneal dialysis disposable and methods of sterilization thereof

A peritoneal dialysis (PD) machine, comprising:

• at least one pump mechanism proximate an interface for a disposable cassette, wherein the disposable cassette includes at least one pump chamber that interfaces with the at least one pump mechanism;
• and
• at least one processor coupled to a memory, the memory storing instructions that, when executed by the at least one processor, cause the PD machine to:
• heat a first volume of a base dialysate solution in a heating region to a temperature sufficient to sterilize components of the disposable cassette, wherein the base dialysate solution includes a mixture of purified water and at least one of electrolytes or dextrose at a first concentration;
• draw the heated base dialysate solution from the heating region into a pump chamber of the disposable cassette;
• and
• pump the heated base dialysate solution into one or more fluid pathways of the disposable cassette to sterilize the one or more fluid pathways.

A method of sterilizing a disposable cassette coupled with a peritoneal dialysis (PD) machine, the method comprising:

• heating a base dialysate solution to a temperature sufficient to sterilize components of the disposable cassette, wherein the base dialysate solution includes a mixture of purified water and at least one of electrolytes or dextrose at a first concentration;
• drawing, using the disposable cassette, a first volume of the heated base dialysate solution into a pump chamber of the disposable cassette;
• and
• pumping the heated base dialysate solution from the pump chamber into one or more fluid pathways within the disposable cassette to sterilize the one or more fluid pathways.