Polyamino Acid Gel Material, Preparation Method Therefor and Use Thereof

Abstract

Provided is a polyamino acid gel material. The material is prepared by performing a pre-crosslinking treatment on an endogenous polyamine and a polyamino acid under the action of an activator, then freezing and crosslinking same, then thawing same at room temperature, and cyclically repeating the freezing-thawing process 0-3 times so as to obtain a polyamino acid gel material. The present disclosure creatively selects the endogenous polyamine and the polyamino acid for pre-crosslinking, and then undergoes the crosslinking reaction under the freezing-thawing conditions so as to generate a scaffold having a continuous interpenetrating porous structure. Such unique structure facilitates the exchange of substances and promotes cellular proliferation and adhesion, has high water absorption. The entire process is mild and controllable, and is high in yield. The present disclosure has potential research values in the field of biomaterials and tissue engineering and wide application prospects.

Dependencies are inferred from the claim text.