Taxane formulations
AssigneeBiopurification, LLC
InventorBahman Shimiaei
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Abstract
Provided is a pharmaceutically acceptable formulation comprising a taxane and an acid-activated 2-hydroxypropyl-β-cyclodextrin (CD). Also provided is a method of treating a patient with a taxane. The method comprises infusing the above formulation into the patient. Additionally provided is a method of preparing the above formulation. Further provided is an infusion bag comprising the above formulation.
Claims21
A pharmaceutically acceptable formulation consisting essentially of a taxane and an acid-activated 2-hydroxypropyl-β-cyclodextrin (CD).
4-6. (canceled)
14-21. (canceled)
23-48. (canceled)
A pharmaceutically acceptable formulation comprising a taxane, an acid-activated 2-hydroxypropyl-β-cyclodextrin (CD) and a sugar.
A pharmaceutically acceptable formulation comprising a taxane and an acid-activated 2-hydroxypropyl-β-cyclodextrin (CD) without a surfactant, polysorbate 80, polyoxyethylated castor oil, a substituted cyclodextrin cellulosic polymer and alcohol.
Dependencies are inferred from the claim text.