Drug loaded modified release pellets

Abstract

A delayed release formulation for delivery of an active pharmaceutical ingredient (API) to the colon comprising pellets with a core and a layered coating on the core, the core comprising the API and the layered coating comprising a first layer comprising a first film forming polymer and a second layer comprising a second film forming polymer, wherein the first film forming polymer is a film forming polymer providing for a pH-dependent release above pH 7.0 and the second film forming polymer is a film forming polymer providing for a pH-independent release.

Dependencies are inferred from the claim text.