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US 2026/0199232 A1Published application
Neuroprotective drug substance-loaded nanomotor formulations
AssigneeHacettepe Universitesi
InventorsHakan EROGLU, Filiz KURALAY, Gizem TEZEL, Elif OZTURK, Selin Seda TIMUR, Reyhan Neslihan GURSOY, Levent ONER, Kezban ULUBAYRAM
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Abstract
A polymer layer containing a pharmaceutical drug substance-loaded amino group and a nanomotor containing a metal layer for orientation by a magnetic field is used to treat Alzheimer's Disease; Memantine HCl-loaded nanomotors are synthesized with a biocompatible poly-L-lysine polymer whose movement is directly controlled by the magnetic field and targets the brain by crossing the blood brain barrier by providing movement in the magnetic field.
Claims14
A nanomotor comprising the following:
- a polymer layer containing an amino group loaded with a pharmaceutical drug substance,
- a metal layer for orientation with a magnetic field.
Dependencies are inferred from the claim text.