Methods and systems for treatment of acute ischemic stroke
AssigneeRoute 92 Medical, Inc.
InventorsMichi E. Garrison, Tony M. Chou
Life of this patent
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Abstract
Described are methods and systems for transcervical access of the cerebral arterial vasculature and treatment of cerebral occlusions, including ischemic stroke. The methods and devices may include methods and devices which may provide aspiration and passive flow reversal, those which protect the cerebral penumbra during the procedure to minimize injury to brain, as well as distal catheters and devices to remove an occlusion. The methods and devices that provide passive flow reversal may also offer to the user a degree of flow control. Devices and methods which provide a way to securely close the access site in the carotid artery to avoid the potentially devastating consequences of a transcervical hematoma are also described.
Claims30
A system of devices for performing a medical procedure at a treatment site in a cerebral vessel of a patient, the system comprising:
- a catheter having a catheter lumen having an inner diameter and a distal end;
- and
- an inner member sized to slide within the catheter lumen, wherein the inner member defines a lumen and has a distal portion and a distal-most end having a distal opening, the distal portion having a first outer diameter that tapers distally to a second outer diameter that is smaller than the first outer diameter,
- wherein the inner member is constructed to have variable stiffness so that the distal portion is made from softer material, with increasingly harder materials towards more proximal sections, and
- wherein the distal portion transitions in flexibility from a flexibility at the second outer diameter to a flexibility at the first outer diameter, and
- wherein the system of devices is in an advancement configuration when the inner member is positioned coaxially in the catheter lumen with the distal portion positioned distal to the distal end of the catheter, and
- wherein flexibility of the system of devices enables the catheter and the inner member to be advanced together distal to a petrous portion of an internal carotid artery to a treatment site in a cerebral vessel while the system of devices is held in the advancement configuration.
An inner member of a system of devices for performing a medical procedure at a treatment site in a cerebral vessel of a patient, the system comprising the inner member and a catheter having catheter lumen having an inner diameter and a distal end,
- wherein the inner member is sized to slide within the catheter lumen, wherein the inner member defines a lumen and has a distal portion and a distal-most end having a distal opening, the distal portion having a first outer diameter than tapers distally to a second outer diameter that is smaller than the first outer diameter,
- wherein the inner member is constructed to have variable stiffness so that the distal portion is made from softer material, with increasingly harder materials towards more proximal sections, and
- wherein the distal portion transitions in flexibility from a flexibility at the second outer diameter to a flexibility at the first outer diameter, and
- wherein the inner member is positionable coaxially in the catheter lumen with the distal portion positioned distal to the distal end of the catheter so that the system of devices is in an advancement configuration, and
- wherein flexibility of the inner member enables the catheter and the inner member to be advanced together distal to a petrous portion of an internal carotid artery to a treatment site in a cerebral vessel while the system of devices is held in the advancement configuration.
Dependencies are inferred from the claim text.