Mri brain image-based system for rapid differentiation of normal pressure hydrocephalus, alzheimer's disease, and normal condition
AssigneesKyungpook National University Industry-Academic Cooperation Foundation, Daegu Catholic University Industry Academic Cooperation Foundation, AICU Corp.
InventorsKYUNG HUN KANG, UI CHEUL YOON, HO SANG YU, EUN AH HWANG
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Abstract
A method for assessing a patient's brain disease state from brain images includes acquiring the brain images, partitioning them into predefined regions based on anatomical landmarks, extracting disease-indicative features, using a pretrained model to generate a disease-associated biomarker from the features, and determining the patient's brain disease state based on the biomarker.
Claims20
A method of assessing a brain disease, the method comprising:
- acquiring a set of brain images of a patient;
- partitioning the brain images into a plurality of predefined regions based on anatomical landmarks;
- extracting feature information from the plurality of regions, wherein the feature information is indicative of a disease state;
- generating, based on a pre-trained brain disease assessment model, a biomarker associated with the disease from the extracted feature information, wherein the biomarker is generated in at least one of the plurality of regions;
- and
- determining a status of the brain disease in the patient based on the biomarker.
A brain disease determination apparatus, comprising:
- a memory storing a brain image processing model trained to generate a biomarker associated with the disease;
- and
- a processor configured to:
- acquire brain images of a patient;
- partition the brain images into a plurality of predefined regions based on anatomical criteria;
- extract feature information for detecting a state of the disease from the plurality of regions;
- generate, based on the brain image processing model, a biomarker associated with the disease from the feature information in at least one of the plurality of regions;
- and
- determine a status of the brain disease in the patient based on the biomarker.
Dependencies are inferred from the claim text.