Anti-microbial antibody signatures related to lung tumors and uses thereof
AssigneeArizona Board of Regents on behalf of Arizona State University
InventorsMahasish SHOME, Ji QIU, Yunro CHUNG, Joshua LABAER
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Abstract
The present invention relates anti-microbial antibody signatures related to lung tumors, including benign tumors and adenocarcinomas. Disclosed herein are antibody panels comprising antigens from bacteria and/or viruses for use in early and accurate diagnosis of lung cancer and for reducing false positive lung carcinoma diagnoses from CT screening.
Claims23
An antibody panel for diagnosing whether a subject has lung carcinoma, the antibody panel comprising at least one antigen from at least one bacterium selected from the group consisting of:
- Helicobacter pylori, Pseudomonas aeruginosa, Streptococcus pneumoniae, Haemophilus influenzae, Streptococcus pyogenes, Mycobacterium tuberculosis, Streptococcus gallolyticus, Fusobacterium nucleatum, Klebsiella pneumoniae, Escherichia coli, Gemella haemolysans, Bacteroides vulgatus, Campylobacter jejuni, Bacteroides fragilis, Peptostreptococcus anaerobius, Citrobacter koseri, Leptotrichia buccalis, Clostridium difficile, Enterococcus faecalis, Porphyromonas gingivalis, Bifidobacterium adolescentis, Prevotella copri, Faecalibacterium prausnitzii, and Veillonella parvula.
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Dependencies are inferred from the claim text.