Methods for performing miniaturized dynamic assays using microfluidics and related systems
AssigneeBiobridge Global
InventorAnand SRINIVASAN
Life of this patent
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Abstract
Some methods of performing an assay comprise culturing target cells in one or more channels of one or more microfluidics chips, where each of the channel(s) can have a volume that is less than or equal to 100 microliters (μL). For each of one or more test liquids that each comprise a therapeutic reagent, the test liquid can flow over the cultured target cells in at least one of the channel(s) and, while the test liquid flows over the cultured target cells, data indicative of an interaction between the target cells over which the test liquid flows and the therapeutic reagent of the test liquid can be captured.
Claims20
A method of performing an assay, the method comprising:
- culturing target cells in one or more channels of one or more microfluidic chips, each of the channel(s) having a volume that is less than or equal to 100 microliters (μL);
- and
- for each of one or more test liquids that each comprise a therapeutic reagent:
- flowing the test liquid over the cultured target cells in at least one of the channel(s);
- and
- while flowing the test liquid over the cultured target cells, capturing data indicative of an interaction between the target cells over which the test liquid flows and the therapeutic reagent of the test liquid.
Dependencies are inferred from the claim text.