Interferometric laser speckle contrast imaging system and method

Abstract

An interferometric laser speckle contrast optical system configured to limit depth of field in order to image only a thin curved object layer of a chosen object while distinguishing such layer from the surrounding curved layers that substantially are not being imaged. The system utilizes a novel 5F-optical arrangement in a sample arm of the constituent interferometer to substantially match the curvature of the surface of illumination with that of the targeted object layer, thereby increasing the spatial resolution and reducing the signal-to-noise ratio of the imaging process. When used as part of an ophthalmoscope, the system for hemodynamic alterations to be measured with substantially capillary level resolution and to establish normative baseline values for retinal neurovascular function.

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