Hyaluronic acid particles and preparation method therefor

Abstract

The present application provides hyaluronic acid particles and a preparation method therefor. The preparation method comprises the following steps: carrying out airflow suspension on a hyaluronic acid raw material, and spraying an adhesive to the suspended hyaluronic acid raw material for granulation to obtain the hyaluronic acid particles, wherein the adhesive is an aqueous solution of water or hyaluronic acid. According to the preparation method of the present application, the dissolution rate of the HA can be significantly increased, the fluidity of the HA can also be improved, thereby avoiding caking, and reducing dust, waste and pollution, and it is more convenient to add the HA into a formula. When the preparation method of the present application is used for preparing the hyaluronic acid particles, three procedures of mixing, granulation and drying can be completed at a time in a container, such that the process route is simplified, the production period is shortened, the cost is reduced, dust is prevented from becoming airborne, and the material loss is reduced. In addition, according to the preparation method of the present application, during granulation, the temperature is relatively low, and the speed is fast, such that the preparation method is very suitable for the granulation of heat-sensitive substances such as hyaluronic acid.

Dependencies are inferred from the claim text.