Cd93 inhibitors

A compound of formula (A)

• wherein
• L is selected from —CO, —SO2 or —(CH2)q,
• Z is selected from any one of the moieties
• R1 is selected from
• —C3-C6 cycloalkyl,
• H,
• C1-C6-alkyl,
• haloalkanes, particularly fluorinated alkanes,
• a heterocycle, wherein the heterocycle comprises 5 or 6 atoms and up to 2 heteroatoms, and
• —COCH3,
• X is selected from
• a heteroaryl,
• phenyl, and
• SP-phenyl or SP-heteroaryl, wherein SP is an alkyne or alkene,
• Rn2 is selected from
• —C1-C4 alkyl, particularly methyl,
• an aromatic moiety (Ar), wherein Ar is an substituted or unsubstituted aryl or substituted or unsubstituted heteroaryl,
• the group of halogens, particularly Br,
• a heterocycle, wherein the heterocycle comprises 5 or 6 atoms and up to 3 heteroatoms, and
• —NMe2, —OMe, —SO2Me, —CONHMe, —NH-Phenyl,
• m is 0 or 1, particularly 0,
• n is 0, 1 or 2, particularly 0 or 1,
• p is 1 or 2,
• q is 0, 1 or 2, particularly 0 or 1.