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US 2026/0193183 A1Published application
N,n-dimethyltryptamine and related psychedelics and uses thereof
AssigneeTerran Biosciences Inc.
InventorsSam CLARK, Matthew Alexander James DUNCTON
Life of this patent
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Abstract
Described herein are compounds that are derivatives of DMT or 5-MeO-DMT and can be metabolically converted to N,N-dimethyltryptamine or analogs thereof upon administration to a subject. In certain embodiments, the compounds described herein are useful for the treatment of conditions associated with a neurological disease.
Claims29
-23. (canceled)
A compound of Formula (Ia), or a pharmaceutically acceptable salt thereof:
- wherein:
- R1 is methoxy or hydrogen;
- and
- R3 is ethyl.
1 more element
A compound of Formula (Ia), or a pharmaceutically acceptable salt thereof:
- wherein:
- R1 is methoxy or hydrogen;
- and
- R3 is alkyl, which is substituted with heteroaryl, which is unsubstituted or substituted with one or more alkyl;
- or
- R3 is cycloalkyl, which is unsubstituted or substituted with —N(R18)R19, heterocycloalkyl, or heteroaryl, which is unsubstituted or substituted with one or more alkyl.
3 more elements
A compound, or a pharmaceutically acceptable salt thereof, wherein the compound is:
Dependencies are inferred from the claim text.