Preparative chromatography system and method for chromatography separations
AssigneeCytiva BioProcess R&D AB
InventorsMatthew Townsend, Ian Scanlon, Ola Lind, Gunnar Malmquist
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Abstract
The present invention relates to a preparative chromatography system 200, 500, 800 and a chromatography process 400, 700 adapted to repetitive cycling of chromatography volumes. The system 200, 500, 800 comprises at least two upstream pumps 203a, 803a, 203b, 803b and separate flow paths 220 from process liquid sources to the chromatography device 200, 500, 800. The system 200, 500, 800 is arranged to prime one flow path 220 with one process liquid while providing another process liquid to the chromatography device and thereby minimizing the hold-up volume of the system 200, 500, 800.
Claims8
A preparative chromatography system incorporating at least one fiber-based chromatography medium and/or at least one membrane based medium and configured to provide at least one convective fluid flow therein.
Dependencies are inferred from the claim text.