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US 2026/0192052 A1Published application
Systems, devices, and methods for delivery of therapies including stabilizing agents
OwnerStephen Harheninventor
Life of this patent
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Abstract
Systems, devices, and methods described herein relate to delivery of therapeutic agents. Such systems and devices can include needle-based delivery systems, in which a stabilizing agent is incorporated into the systems for controlling gas transmission into and out of the primary drug container of the therapeutic agent.
Claims28
An apparatus, comprising:
- a needle having a proximal end and a distal end;
- a primary container having a body, a plunger, and a seal, the body, the plunger, and the seal collectively defining a reservoir configured to contain a therapeutic agent solution;
- an intermediary fluid including a stabilizing agent configured to slow an escape of hydrogen sulfide gas transmission through at least a portion of the primary container;
- a stored energy device configured to apply pressure to the intermediary fluid;
- and
- an activation device configured to activate the stored energy device to apply pressure to the intermediary fluid such that the intermediary fluid acts on the primary container to drive a movement of the plunger to extrude the therapeutic agent solution out through the needle.
3 more elements
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An apparatus, comprising:
- a needle having a proximal end and a distal end;
- a primary container having a body, a plunger, and a seal, the body, the plunger, and the seal collectively defining a reservoir configured to contain a therapeutic agent solution;
- an intermediary fluid including a stabilizing chemical agent to slow a rate of oxygen penetration into the therapeutic agent solution via gas transmission through at least a portion of the primary container;
- a stored energy device configured to apply pressure to the intermediary fluid;
- and
- an activation device configured to activate the stored energy device to apply pressure to the intermediary fluid such that the intermediary fluid acts on a cartridge to drive a movement of the plunger to extrude the therapeutic agent solution out through the needle.
3 more elements
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(canceled)
(canceled)
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An apparatus, comprising:
- a needle having a proximal end and a distal end;
- a primary container having a body, a plunger, and a seal, the body, the plunger, and the seal collectively defining a reservoir configured to contain a therapeutic agent solution;
- an intermediary fluid including a stabilizing chemical agent configured to increase a shelf-life of the therapeutic agent solution;
- a stored energy device configured to apply pressure to the intermediary fluid;
- and
- an activation device configured to activate the stored energy device to apply pressure to the intermediary fluid such that the intermediary fluid acts on a cartridge to drive a movement of the plunger to extrude the therapeutic agent solution out through the needle.
3 more elements
(canceled)
(canceled)
Dependencies are inferred from the claim text.