Affordable universal fusion universal vaccine for foot and mouth disease infections
OwnerMatthias Magoolainventor
Life of this patent
Estimating the term…
Loading patent…
OwnerMatthias Magoolainventor
Estimating the term…
The present invention relates to a pharmaceutical composition for inducing one or more immune responses capable of cross-protection against multiple strains or serotypes of a virus to generate protection with a single vaccination campaign. This universal vaccine comprises a composition presenting epitopes of antigens of all known sera of A, O, C, Asia, and the South African types of SAT-1, 2, and 3 capable of developing immunity against the Foot and Mouth Disease (FMD) in food-producing animals, such as cattle, sheep, goats, swine and other cloven-hoofed animals. The antigen vaccine is fused with serum proteins or short peptides to bind to serum proteins to enhance its half-life and with an adjuvant to enhance the activity of the vaccine when produced using recombinant technology. The RNA-based delivery of vaccines reduces the cost significantly, making this universal fusion vaccine affordable globally.
A fusion universal vaccine formulation capable of inducing cross-protection against different serotypes or strains of Food and Mouth Disease virus (FMDV), comprising recombinant or RNA-delivered peptides, polypeptides, or proteins of known sera of the said FMDV fused with serum proteins to extend the half-life of the antigen.
Dependencies are inferred from the claim text.