Disposable personal care products composed of nonwoven fabrics coated with bacteriophages to prevent and reduce bacterially caused skin problems
AssigneeParallel Health, Inc.
InventorsNathan BROWN, Natalise Kalea ROBINSON
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Abstract
Provided herein are compositions of phage combinations attached to surface-active polymer fabrics. The polymer fabrics may be integrated into personal care products. Provided herein are also methods for attaching the phage combinations onto the surface-active polymer fabrics. Methods for selecting the phage combinations are also described. Also provided are methods for using the composition of phage combinations for treating one or more skin conditions.
Claims58
A composition comprising a phage combination attached to a polymeric fabric,
- wherein the phage combination comprises one or more sets of phages that infect one or more bacterial species,
- wherein the phages are selected from Myoviridae, Podoviridae and Siphoviridae, and
- wherein the polymeric fabric is selected from at least one of a polyhydroxybutyrate (PHB) or a polyethylene terephthalate (PET) nonwoven fabric.
A composition comprising a phage combination attached to a polymeric fabric,
- wherein the phage combination comprises one or more sets of Caudoviricetes phages, and
- wherein the polymeric fabric is a polyethylene terephthalate (PET) nonwoven fabric.
A composition comprising a phage combination attached to a polymeric fabric,
- wherein the phage combination comprises at least Staphylococcus aureus infecting phages, and
- wherein the polymeric fabric is selected from at least one of a polyhydroxybutyrate (PHB) or a polyethylene terephthalate (PET) nonwoven fabric.
A composition comprising a phage combination attached to a polymeric fabric,
- wherein the phage combination comprises at least Escherichia coli infecting phages, and
- wherein the polymeric fabric is selected from at least one of a polyhydroxybutyrate (PHB) or a polyethylene terephthalate (PET) nonwoven fabric.
A composition comprising a phage combination attached to a polymeric fabric,
- wherein the phage combination comprises one or more sets of Caudoviricetes phages, and
- wherein the polymeric fabric is selected from the group consisting of a polylactic acid (PLA), polyester (PE), polycaprolactone (PCL), acrylics, olefins, polyhydroxyalkanoates (PHA), polyhydroxybutyrate (PHB), polyethylene terephthalate (PET), polypropylene (PP), and polypropylene carbonate (PPC) nonwoven fabric.
A composition comprising a phage combination attached to a polymeric fabric, wherein the phage combination comprises one or more sets of phages that infect one or more bacterial species.
A method of preparing a personal care product, the method comprising
- (a) contacting a nonwoven polymeric fabric with a composition comprising a phage combination,
- wherein the phage combination comprises one or more sets of phages of Caudoviricetes phages that infect one or more bacterial species, and
- wherein the nonwoven polymeric fabric is selected from at least one of a polyhydroxybutyrate (PHB) or a polyethylene terephthalate (PET) nonwoven fabric.
A method of preparing a personal care product, the method comprising
- (a) contacting a nonwoven polymeric fabric with a plasma composition to generate a plasma-treated nonwoven fabric,
- wherein the nonwoven polymeric fabric is selected from at least one of a polyhydroxybutyrate (PHB) or a polyethylene terephthalate (PET) nonwoven fabric;
- (b) immobilizing a combination of phages comprising at least one or more sets of Caudoviricetes phages onto the nonwoven polymeric fabric,
- wherein the phage combination comprises one or more sets of phages that infect one or more bacterial species;
- and
- (c) incorporating the nonwoven polymeric fabric into the personal care product.
A nonwoven polymeric fabric comprising a phage combination attached to the polymeric fabric,
- wherein the phage combination comprises one or more sets of Caudoviricetes phages that infect one or more bacterial species, and
- wherein the polymeric fabric is selected from a polylactic acid (PLA), polyester (PE), acrylics, olefins, polyhydroxyalkanoates (PHA), polyhydroxybutyrate (PHB), polyethylene terephthalate (PET), polypropylene (PP) and polypropylene carbonate (PPC) nonwoven fabric.
Manufacturing of a personal care product for reducing contact dermatitis, reducing skin infection and/or reducing body odor, the personal care product comprising a nonwoven polymeric fabric,
- wherein the nonwoven polymeric fabric comprises a phage combination attached to the nonwoven fabric selected from at least one of a polyhydroxybutyrate (PHB) or a polyethylene terephthalate (PET) nonwoven fabric, and
- wherein the phage combination comprises one or more sets of Caudoviricetes phages that infect one or more bacterial species.
Dependencies are inferred from the claim text.