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US 2026/0185994 A1Published application
Systems and Methods of Oral Cancer Assessment Using Cellular Phenotype Data
AssigneeNew York University
InventorsJohn T. McDevitt, Michael P. McRae
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Abstract
The present disclosure is related to systems and methods to be used as aids in the diagnosis of risk for oral cancer by identifying cellular phenotype characteristics of a noninvasive brush biopsy sample.
Claims6
A software stored on a non-transitory computer-readable medium, wherein the software:
- identifies the cellular phenotype of one or more cells in a sample of a subject;
- determines one or more cellular phenotype characteristics of the sample based upon the identified cellular phenotype of the cells;
- and
- uses the cellular phenotype characteristics to assess the presence or severity of oral cancer in the subject.
1 more element
A system comprising a cartridge and a separate reader,
- the cartridge comprising a generally flat substrate having embedded microfluidic channels connecting an inlet port to an embedded downstream assay chamber, wherein the assay chamber comprises a membrane for collection of cells administered to cartridge via the inlet port;
- the reader comprising a non-transitory computer-readable medium having software stored thereon, which performs steps comprising:
- identifying the cellular phenotype of one or more cells in a sample of a subject;
- determining one or more cellular phenotype characteristics of the sample based upon the identified cellular phenotype of the cells;
- and
- using the cellular phenotype characteristics to assess the presence or severity of oral cancer in the subject.
3 more elements
Dependencies are inferred from the claim text.