Reactive granulation of calcium citrate malate, dicalcium malate, and dimagnesium malate

A method for preparing granules of calcium citrate malate, the method comprising:

• contacting citric acid and malic acid forming a particulate mixture;
• adding water to the particulate mixture from step (a) forming a slurry;
• contacting a calcium base with the slurry from step (b);
• reacting to form the granules of calcium citrate malate;
• and
• isolating the granules of calcium citrate malate;
• wherein the granules of calcium citrate malate have a water content of at least 5.0 wt %.

A method for preparing granules of dicalcium malate, the method comprising:

• adding water to a calcium base forming a slurry;
• contacting the slurry from step (a) with malic acid causing a reaction between the malic acid and the calcium base forming a second slurry;
• repeating step (b) until the calcium base and malic acid fully react forming granules of dicalcium malate;
• and
• isolating the granules of dicalcium malate;
• wherein the granules of dicalcium malate have a water content of at least 5.0 wt %.

A method for preparing granules of dimagnesium malate, the method comprising:

• contacting a magnesium base and a malic acid forming a particulate mixture;
• adding water to the particulate mixture from step (a) causing a partial reaction between the malic acid and the magnesium base forming a slurry;
• repeating step (b) until the malic acid and the magnesium base fully react forming granules;
• and
• isolating the granules of dimagnesium malate;
• wherein the granules of dimagnesium malate have a water content of at least 2.0 wt %.